Magnesium supplementation in pregnancy. A double-blind study
The effect of magnesium supplementation in pregnancy was studied in 568 women who were treated with 15 mol magnesium-aspartate-hydrochloride per day for aspartic acid as placebo given orally during pregnancy from < = 16 weeks. Allocation to the two groups was performed according to the women's birth dates. Magnesium supplementation during pregnancy was associated with significantly fewer maternal hospitalizations, a reduction in preterm delivery, and less frequent referral of newborn to the neonatal intensive care unit. The results suggest that magnesium supplementation during pregnancy has a significant influence on fetal and maternal morbidity both before and after delivery.